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VEGFC antibody (Vascular Endothelial Growth Factor C) (C-Term)

Details for Product anti-VEGFC Antibody No. ABIN387759, Supplier: Login to see New
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Synonyms VEGFC, vegf-c, xvegf-c, Flt4-L, VRP, AW228853, VEGF-C
C-Term, N-Term
(25), (17), (15), (13), (13), (11), (11), (8), (6), (5), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Human, Mouse (Murine)
(169), (60), (45), (4), (3), (2), (2), (1), (1), (1), (1), (1)
(174), (50), (9), (1)
Clonality (Clone)
Monoclonal ()
This VEGFC antibody is un-conjugated
(20), (19), (15), (7), (7), (7), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(175), (112), (83), (27), (22), (11), (11), (10), (6), (5), (3), (1)
Pubmed 5 references available
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Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This monoclonal antibody is generated from mice immunized with three KLH conjugated synthetic peptides selected from the N-terminal, central, and C-terminal regions of human VEGF3.
Clone 30AT1174-77
Isotype IgG1
Specificity This monoclonal antibody is generated from mice immunized with three KLH conjugated synthetic peptides selected from the N-terminal, central, and C-terminal regions of human VEGF3.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name VEGF3 (VEGFC Antibody Abstract)
Background The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
Synonyms: Vascular Endothelial Growth Factor C, VEGF-C, Vascular endothelial growth factor-related protein, VRP, Flt4 ligand, Flt4-L, VEGF3
Molecular Weight 46883 DA
Gene ID 7424
UniProt P49767
Research Area Cell Signaling, Cell Structure, Cancer, Cell Cycle
Pathways RTK Signaling
Application Notes WB = 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-VEGFC antibody (Vascular Endothelial Growth Factor C) (C-Term) (ABIN387759) Western analysis of extracts from HDMEC cells using VEGF3 antibody.
Background publications Romero, Friel, Velez Edwards et al.: "A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)." in: American journal of obstetrics and gynecology, Vol. 203, Issue 4, pp. 361.e1-361.e30, 2010 (PubMed).

Deguchi, Ichikawa, Soga et al.: "Clinical significance of vascular endothelial growth factors C and D and chemokine receptor CCR7 in gastric cancer." in: Anticancer research, Vol. 30, Issue 6, pp. 2361-6, 2010 (PubMed).

Johnatty, Beesley, Chen et al.: "Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot"." in: PLoS genetics, Vol. 6, Issue 7, pp. e1001016, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Romero, Velez Edwards, Kusanovic et al.: "Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes." in: American journal of obstetrics and gynecology, Vol. 202, Issue 5, pp. 431.e1-34, 2010 (PubMed).

Catalog No. ABIN387759
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