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VEGFC Products

(Vascular Endothelial Growth Factor C (VEGFC))
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D. [provided by RefSeq, Jul 2008].

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Featured VEGFC Categories

VEGFC Antibodies

High quality antibodies with extensive validation data.

VEGFC ELISA Kits

Reliable ELISA kits for a wide range of species.

VEGFC Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended VEGFC Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7429439
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (3)
  • (3)
Cat. No. ABIN731723
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN655891
Quantity 400 μL
Datasheet Datasheet

Recommended VEGFC ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
Cat. No. ABIN6960462
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
Cat. No. ABIN6960463
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (10)
  • (1)
Cat. No. ABIN411382
Quantity 96 tests
Datasheet Datasheet

Recommended VEGFC Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7275829
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275830
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1324984
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our VEGFC products

Shi, Wei, Zhu, Yan, Wang, Zhang, Li, Zheng, Yuan, Lu, Yuan: "The RNA-binding protein QKI suppresses tumorigenesis of clear cell renal cell carcinoma by regulating the expression of HIF-1α." in: Journal of Cancer, Vol. 11, Issue 6, pp. 1359-1370, (2020) (PubMed).

Jha, Rauniyar, Chronowska, Mattonet, Maina, Koistinen, Stenman, Alitalo, Jeltsch: "KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D." in: eLife, Vol. 8, (2019) (PubMed).

Sopo, Anttila, Hämäläinen, Kivelä, Ylä-Herttuala, Kosma, Keski-Nisula, Sallinen: "Expression profiles of VEGF-A, VEGF-D and VEGFR1 are higher in distant metastases than in matched primary high grade epithelial ovarian cancer." in: BMC cancer, Vol. 19, Issue 1, pp. 584, (2019) (PubMed).

Podemska-Jedrzejczak, Malinska, Sujka-Kordowska, Nowicki, Puslecki, Jemielity, Perek: "Vascular restenosis in coronary artery bypass grafting might be associated with VEGF-C/VEGFR-3 signaling pathway." in: Heart and vessels, Vol. 33, Issue 9, pp. 1106-1120, (2018) (PubMed).

Xiong, Liu, Zhao, Ruan, Zhang, Wang, Huang: "CPT1A regulates breast cancer-associated lymphangiogenesis via VEGF signaling." in: Biomedicine & pharmacotherapy, Vol. 106, pp. 1-7, (2018) (PubMed).

Dai, Cui, Zhang, Cheng, Liu, Yang, Fan, Wang, Lin, Zhang, Li, Mao, Wang, Su, Zhang, Peng, Yang, Hu, Yang, Huang, Xiang, Yu, Zhou, Wei, Deng: "SARI inhibits angiogenesis and tumour growth of human colon cancer through directly targeting ceruloplasmin." in: Nature communications, Vol. 7, pp. 11996, (2018) (PubMed).

Zhu, Huang, Huang, Zheng, Hua, Yang, Zhuang, Wang, Ye: "Lipopolysaccharide increases the release of VEGF-C that enhances cell motility and promotes lymphangiogenesis and lymphatic metastasis through the TLR4- NF-κB/JNK pathways in colorectal cancer." in: Oncotarget, Vol. 7, Issue 45, pp. 73711-73724, (2018) (PubMed).

Chen, Liu, Zhang, Gao, Zhang, Shen, Li, Shen: "Effects of diphyllin as a novel V-ATPase inhibitor on TE-1 and ECA-109 cells." in: Oncology reports, Vol. 39, Issue 3, pp. 921-928, (2018) (PubMed).

Dingle, Yap, Gerrand, Taylor, Keramidaris, Lokmic, Kong, Peters, Morrison, Mitchell: "Characterization of isolated liver sinusoidal endothelial cells for liver bioengineering." in: Angiogenesis, Vol. 21, Issue 3, pp. 581-597, (2018) (PubMed).

Bai, Wang, Han, Xie, Ji, Yin, Chen, Wang, Jiang, Qi, Jiang: "BCL2L10 inhibits growth and metastasis of hepatocellular carcinoma both in vitro and in vivo." in: Molecular carcinogenesis, Vol. 56, Issue 3, pp. 1137-1149, (2017) (PubMed).

Synonyms and alternative names related to VEGFC

vascular endothelial growth factor c (vegfc), vascular endothelial growth factor C (VEGFC), vascular endothelial growth factor C S homeolog (vegfc.S), vascular endothelial growth factor C (Vegfc), AW228853, Flt4-L, vegf-c, VEGF-C, VEGFC, VRP, xvegf-c

Protein level used designations for VEGFC

  • vascular endothelial growth factor C
  • vascular endothelial growth factor c
  • FLT4 ligand DHM
  • VEGF-C
  • vascular endothelial growth factor-related protein
  • VRP
  • flt4 ligand
  • flt4-L
  • vascular endothelial growth factor C isoform 129
  • vascular endothelial growth factor C isoform 184
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