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Details for Product No. ABIN388854

Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (C-Term), (AA 123-153) antibody

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Antigen
Synonyms RIG-B, UBCH8, Ubce8, Ubcm8, 2810489I21Rik, UbcM8, UBE2L6
Epitope
»Alternatives C-Term, AA 123-153
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN388854
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-153 AA from the C-terminal region of human UBE2L6.
Clone RB4157
Isotype Ig
Specificity This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124~153 amino acids from the C-terminal region of human UBE2L6.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name UBE2L6
Background The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.
Synonyms: Ubiquitin/ISG15-conjugating enzyme E2 L6, Ubiquitin-protein ligase L6, Ubiquitin carrier protein L6, UbcH8, Retinoic acid-induced gene B protein, RIG-B
Molecular Weight 17637 DA
Gene ID 9246
UniProt O14933
Research Area Ubiquitin-related antibodies, Cell Signaling, Protein Modifications, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Kumar, Kao, Howley: "Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity." in: The Journal of biological chemistry, Vol. 272, Issue 21, pp. 13548-54, 1997 (PubMed).

Alternatives for antigen "Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6)", type "Antibodies"
Hosts (28), (18)
Reactivities (48), (13), (13), (1), (1), (1)
Applications (35), (25), (12), (10), (6), (3), (3), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (7), (5), (4), (3), (1), (1), (1)
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