Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (AA 1-152), (N-Term) antibody

Details for Product No. ABIN317574, Supplier: Log in to see
Antigen
  • UBE2L6
  • RIG-B
  • UBCH8
  • 2810489I21Rik
  • Ubce8
  • Ubcm8
  • UbcM8
  • ubiquitin conjugating enzyme E2 L6
  • ubiquitin-conjugating enzyme E2L 6
  • UBE2L6
  • Ube2l6
Epitope
AA 1-152, N-Term
15
12
11
11
7
7
4
4
2
2
1
Reactivity
Human
78
6
5
3
3
2
2
2
1
1
1
Host
Mouse
55
23
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
69
45
30
11
6
3
3
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Recombinant human UBE2L6 (1-152 aa) purified from E. coli
Clone K1H3
Isotype IgG2b
Specificity The antibody recognizes human UBE2L6. Other species not tested.
Characteristics Synonyms: Ubiquitin/ISG15-conjugating enzyme E2 L6, Ubiquitin-protein ligase L6, Ubiquitin carrierprotein L6, UBCH8, Retinoic acid-induced gene B protein
Purification Protein-G affinity chromatography
Antigen Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6)
Alternative Name UBE2L6 / RIG-B (UBE2L6 Antibody Abstract)
Background Ubiquitin-conjugating enzyme E2L6 (UBE2L6), also known as UbcH8, is a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination of a protein substrate requires the concerted action of 3 classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin protein ligases. The E2 ubiquitin-conjugating enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene.Synonyms: Retinoic acid-induced gene B protein, UBCH8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6, Ubiquitin/ISG15-conjugating enzyme E2 L6
Gene ID 9246
UniProt O14933
Application Notes ELISA. Western blot (1: 1,000 - 1: 3,000), recommended starting dilution is 1: 2,000. Immunohistochemistry on Paraffin embedded tissue (1: 50 - 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (AA 1-152), (N-Term) antibody (ABIN317574) anti-Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (AA 1-152), (N-Term) antibody
Immunohistochemistry (IHC) image for anti-Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (AA 1-152), (N-Term) antibody (ABIN317574) anti-Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (AA 1-152), (N-Term) antibody (Image 2)
Western Blotting (WB) image for anti-Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (AA 1-152), (N-Term) antibody (ABIN317574) anti-Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (AA 1-152), (N-Term) antibody (Image 3)
Immunohistochemistry (IHC) image for anti-Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (AA 1-152), (N-Term) antibody (ABIN317574) anti-Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (AA 1-152), (N-Term) antibody (Image 4)
Background publications Ardley, Rose, Tan, Leek, Markham, Robinson: "Genomic organization of the human ubiquitin-conjugating enzyme gene, UBE2L6 on chromosome 11q12." in: Cytogenetics and cell genetics, Vol. 89, Issue 1-2, pp. 137-40, 2000 (PubMed).

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