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Details for Product No. ABIN390178

Sirtuin 3 (SIRT3) (C-Term), (AA 250-279) antibody

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Antigen
Synonyms SIR2L3, zgc:158774, 2310003L23Rik, AI848213, Sir2l3, sirtuin
Epitope
»Alternatives C-Term, AA 250-279
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN390178
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This SIRT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 AA from the C-terminal region of human SIRT3.
Clone RB01967
Isotype Ig
Specificity This polyclonal antibody was raised against a peptide selected from the C-terminal region of human Sirt3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SIRT3
Background Synonyms: SIR2-like protein 3, mSIR2L3, NAD-dependent deacetylase sirtuin-3,Sir2l3, Sirt3
Molecular Weight 43573 DA
Gene ID 23410
UniProt Q9NTG7
Research Area Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Pillai, Sundaresan, Kim et al.: "Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway." in: The Journal of biological chemistry, Vol. 285, Issue 5, pp. 3133-44, 2010 (PubMed).

Kawamura, Uchijima, Horike et al.: "Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest." in: The Journal of clinical investigation, 2010 (PubMed).

Alternatives for antigen "Sirtuin 3 (SIRT3)", type "Antibodies"
Hosts (61), (9), (8), (4)
Reactivities (69), (32), (25), (14), (12), (3), (2), (1), (1), (1), (1), (1), (1)
Applications (68), (42), (12), (11), (10), (7), (4), (3), (2), (1), (1)
Conjugates (6), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (20), (6), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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