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Details for Product No. ABIN390473

Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (N-Term), (AA 27-56) antibody

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EIF2C, EIF2C1, GERP95, Q99, Eif2c1, ARGONAUTE 1, T1N15.2, T1N15_2, Ago, Ago-1, Ago1, CG6671, Dm Ago1, Dmel\\CG6671, MRE20, ago1, ago1-1, anon-WO0257455.29, dAGO1, dAgo1, l(2)04845, l(2)4845, l(2)k0020 ... show more
»Alternatives N-Term, AA 27-56
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN390473
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This AGO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-56 AA from the N-terminal region of human AGO1.
Clone RB18965
Isotype Ig
Specificity This AGO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34~64 amino acids from the N-terminal region of human AGO1.
Predicted Reactivity Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name AGO1
Background AGO1 is a member of the Argonaute family of proteins which play a role in RNA interference. The protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing.
Synonyms: Protein argonaute-1, Argonaute1, hAgo1, Eukaryotic translation initiation factor 2C 1, eIF-2C 1, eIF2C 1, Putative RNA-binding protein Q99, AGO1, EIF2C1
Molecular Weight 97214 DA
Gene ID 26523
UniProt Q9UL18
Research Area Transcription Factors, Signaling
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Horikawa, Wood, Yang et al.: "Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 23, pp. 7956-62, 2008 (PubMed).

Weinmann, Höck, Ivacevic et al.: "Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs." in: Cell, Vol. 136, Issue 3, pp. 496-507, 2009 (PubMed).

Alternatives for antigen "Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1)", type "Antibodies"
Hosts (23), (7), (2), (1)
Reactivities (29), (17), (17), (11), (11), (11), (3), (1), (1)
Applications (20), (12), (9), (7), (5), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (4), (1), (1)