Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN390649

O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT) (C-Term), (AA 1017-1046) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms HRNT1, O-GLCNAC, 1110038P24Rik, 4831420N21Rik, AI115525, Ogtl, BcDNA:GH04245, CG10392, Dmel\\CG10392, OGT, Ogt, P1201, SXC, Sxc, l(2)02637, l(2)NC130, sxc/Ogt, fm81g08, ogt, wu:fc12b01, wu:fm81g08
Epitope
»Alternatives C-Term, AA 1017-1046
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN390649
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen This OGT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1017-1046 AA from the C-terminal region of human OGT.
Clone RB18524
Isotype Ig
Specificity This OGT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1017~1046 amino acids from the C-terminal region of human OGT.
Predicted Reactivity Pig (Porcine),Rat (Rattus),Rabbit
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name OGT
Background O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal.
Synonyms: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, O-linked N-acetylglucosamine transferase 110 kDa subunit, O-GlcNAc transferase subunit p110, OGT
Molecular Weight 116925 DA
Gene ID 8473
UniProt O15294
Research Area Cancer, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Slawson, Lakshmanan, Knapp et al.: "A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin." in: Molecular biology of the cell, Vol. 19, Issue 10, pp. 4130-40, 2008 (PubMed).

Taylor, Geisler, Chambers et al.: "Up-regulation of O-GlcNAc transferase with glucose deprivation in HepG2 cells is mediated by decreased hexosamine pathway flux." in: The Journal of biological chemistry, Vol. 284, Issue 6, pp. 3425-32, 2009 (PubMed).

Fujiki, Chikanishi, Hashiba et al.: "GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis." in: Nature, Vol. 459, Issue 7245, pp. 455-9, 2009 (PubMed).

Alternatives for antigen "O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT)", type "Antibodies"
Hosts (17), (9), (3)
Reactivities (23), (13), (10), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applications (28), (13), (10), (8), (3), (3), (3), (1)
Epitopes (5), (3), (2), (2), (1), (1)
Beacon