OGT antibody (AA 857-1036)

Catalog No. ABIN3022708

The Rabbit Polyclonal anti-OGT antibody (ABIN3022708) specifically detects OGT in WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for OGT antibody (AA 857-1036) (ABIN3022708)

Target: OGT (O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OGT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-OGT Antibody

Binding Specificity: AA 857-1036

Sequence: RVPNSVLWLL RFPAVGEPNI QQYAQNMGLP QNRIIFSPVA PKEEHVRRGQ LADVCLDTPL CNGHTTGMDV LWAGTPMVTM PGETLASRVA ASQLTCLGCL ELIAKNRQEY EDIAVKLGTD LEYLKKVRGK VWKQRISSPL FNTKQYTMEL ERLYLQMWEH YAAGNKPDHM IKPVEVTESA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 857-1036 of human OGT (NP_858059.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OGT

Target: OGT (O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT))

Alternative Name: OGT

Background: This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,OGT,HINCUT-1,HRNT1,O-GLCNAC,MRX106,OGT1,Signal Transduction,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,OGT

Molecular Weight: 74 kDa/103 kDa/115 kDa/116 kDa

Gene ID: 8473

UniProt: O15294

Pathways: Regulation of Carbohydrate Metabolic Process