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Details for Product No. ABIN390866

Fragile X Mental Retardation Syndrome 1 (FMR1) (N-Term), (AA 20-48) antibody

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Synonyms zFMR1
»Alternatives N-Term, AA 20-48
»Alternatives Human, Mouse (Murine)
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN390866
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This FMR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-48 AA from the N-terminal region of human FMR1.
Clone RB20964
Isotype Ig
Specificity This FMR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27~56 amino acids from the N-terminal region of human FMR1. Note: It was reported by a customer that in addition to the target band, this antibody also recognizes a ~40KD band in mouse cerebellum. This ~40kd band might account for part of the IHC staining in mouse cerebellum.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FMR1
Background FMR1 binds RNA and is associated with polysomes. This protein may be involved in mRNA trafficking from the nucleus to the cytoplasm.
Synonyms: Fragile X mental retardation 1 protein, Protein FMR-1, FMRP, FMR1
Molecular Weight 71174 DA
Gene ID 2332
UniProt Q06787
Research Area Signaling, Protein Modifications, Neurology
Application Notes Recommend dilutions: IHC : 1:50-100,WB : 1:1000,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Yuhas, Walichiewicz, Pan et al.: "High-risk fragile x screening in Guatemala: use of a new blood spot polymerase chain reaction technique." in: Genetic testing and molecular biomarkers, Vol. 13, Issue 6, pp. 855-9, 2009 (PubMed).

Alternatives for antigen "Fragile X Mental Retardation Syndrome 1 (FMR1)", type "Antibodies"
Hosts (18), (9), (6)
Reactivities (26), (5), (3), (3), (3), (2), (1), (1)
Applications (29), (14), (12), (10), (6), (5), (3), (2), (1)
Epitopes (4), (2), (2), (1), (1)