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FMR1 antibody (AA 1-290)
FMR1
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-FMR1 Antibody
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Target
See all FMR1 Antibodies
FMR1
(Fragile X Mental Retardation 1 (FMR1))
Binding Specificity
All epitopes for FMR1 antibodies
AA 1-290
Reactivity
All reactivities for FMR1 antibodies
Human
Host
All hosts for FMR1 antibodies
Rabbit
Clonality
All clonalities for FMR1 antibodies
Polyclonal
Conjugate
All conjugates for FMR1 antibodies
This FMR1 antibody is un-conjugated
Application
All applications for FMR1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
MEELVVEVRG SNGAFYKAFV KDVHEDSITV AFENNWQPDR QIPFHDVRFP PPVGYNKDIN ESDEVEVYSR ANEKEPCCWW LAKVRMIKGE FYVIEYAACD ATYNEIVTIE RLRSVNPNKP ATKDTFHKIK LDVPEDLRQM CAKEAAHKDF KKAVGAFSVT YDPENYQLVI LSINEVTSKR AHMLIDMHFR SLRTKLSLIM RNEEASKQLE SSRQLASRFH EQFIVREDLM GLAIGTHGAN IQQARKVPGV TAIDLDEDTC TFHIYGEDQD AVKKARSFLE FAEDVIQVPR
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human FMRP (NP_001172011.1).
Isotype
IgG
Top Product
Discover our top product FMR1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for FMR1
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Target
FMR1
(Fragile X Mental Retardation 1 (FMR1))
Alternative Name
FMR1 (FMR1 Products )
Synonyms
AT24755 antibody, BcDNA:GM08679 antibody, CG6203 antibody, Dmel\\CG6203 antibody, EP(3)3517 antibody, FMR antibody, FMR1 antibody, FMRP antibody, FMRp antibody, FXR antibody, Fmrp antibody, cg6203 antibody, dFMR antibody, dFMR1 antibody, dFMRP antibody, dFXR antibody, dFXR1 antibody, dFXRP antibody, dFmr1 antibody, dFmrp antibody, dfmr antibody, dfmr1 antibody, dfxr antibody, dfxr1 antibody, dmfr1 antibody, fmr antibody, fmr1 antibody, FRAXA antibody, POF antibody, POF1 antibody, zFMR1 antibody, Fmr-1 antibody, CG6203 gene product from transcript CG6203-RC antibody, fragile X mental retardation 1 antibody, fragile X mental retardation syndrome 1 antibody, Fmr1 antibody, FMR1 antibody, fmr1 antibody
Background
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.,FMRP,FRAXA,POF,POF1,FMR1,POFX,Epigenetics & Nuclear Signaling,RNA Binding,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Neuron marker,Dendrite marker,Synapse marker,FMR1
Molecular Weight
58 kDa/61 kDa/66 kDa/68 kDa/69 kDa/70 kDa/71 kDa
Gene ID
2332
UniProt
Q06787
Pathways
Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development
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