Signal Recognition Particle 72kDa (SRP72) (AA 119-148), (Center) antibody

Details for Product No. ABIN390903
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Antigen
Synonyms CG5434, Dmel\\CG5434, wu:fi03d11, 5730576P14Rik, 72kDa, AI132477, BC019196, C77589, BMFF
Epitope
AA 119-148, Center
(9), (3), (2), (1), (1)
Reactivity
Human
(16), (2), (2), (2), (2), (2), (2), (1), (1)
Host
Rabbit
(15), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
(16), (8), (8), (4), (3), (3), (1), (1)
Pubmed 1 reference available
Quantity 400 μL
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Catalog No. ABIN390903
291.50 $
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Immunogen This SRP72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 AA from the Central region of human SRP72.
Clone RB21267
Isotype Ig
Specificity This SRP72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126~156 amino acids from the Center region of human SRP72.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SRP72
Background Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. It binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
Synonyms: Signal recognition particle 72 kDa protein, SRP72, SRP72
Molecular Weight 74606 DA
Gene ID 6731
UniProt O76094
Research Area Signaling, Protein Modifications, Neurology
Application Notes FACS = 1:10-50, WB = 1:1000, IHC = 1:50-100, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Signal Recognition Particle 72kDa (SRP72) (AA 119-148), (Center) antibody Western blot analysis of SRP72 Antibody (Center) (ABIN390903) in Hela cell line lysates (35 µg/lane). SRP72 (arrow) was detected using the purified polyclonal antibody.
anti-Signal Recognition Particle 72kDa (SRP72) (AA 119-148), (Center) antibody (2) Formalin-fixed and paraffin-embedded human pancreas with SRP72 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Background publications Utz, Hottelet, Le et al.: "The 72-kDa component of signal recognition particle is cleaved during apoptosis." in: The Journal of biological chemistry, Vol. 273, Issue 52, pp. 35362-70, 1999 (PubMed).

Validation Images
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