SRP72 antibody (AA 621-671)

Catalog No. ABIN7453212

Product Details anti-SRP72 Antibody

Target: SRP72 (Signal Recognition Particle 72kDa (SRP72))

Binding Specificity: AA 621-671

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRP72 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit anti-SRP72 Antibody, Affinity Purified

Predicted Reactivity: Dog

Purification: Affinity Purified

Immunogen: Between AA 621 and 671

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SRP72

Target: SRP72 (Signal Recognition Particle 72kDa (SRP72))

Alternative Name: SRP72 (SRP72 Products)

Synonyms: CG5434 antibody, Dmel\\CG5434 antibody, wu:fi03d11 antibody, 5730576P14Rik antibody, 72kDa antibody, AI132477 antibody, BC019196 antibody, C77589 antibody, BMFF antibody, Signal recognition particle protein 72 antibody, signal recognition particle 72 antibody, signal recognition particle 72kDa antibody, signal recognition particle subunit Srp72 (predicted) antibody, part of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex antibody, type II secretory pathway family antibody, signal recognition particle 72kDa S homeolog antibody, Srp72 antibody, SRP72 antibody, srp72 antibody, srp72.S antibody

Background: Background: Signal recognition particle subunit SRP72 is the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure [taken from NCBI Entrez Gene (Gene ID: 6731)].

Gene ID: 6731

NCBI Accession: NP_008878

UniProt: O76094

Pathways: SARS-CoV-2 Protein Interactome