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CYP3A4 antibody (AA 228-255)

CYP3A4 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB15792 unconjugated
Catalog No. ABIN392216
  • Target See all CYP3A4 Antibodies
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    Binding Specificity
    • 16
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 228-255
    Reactivity
    • 97
    • 43
    • 34
    • 18
    • 16
    • 13
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 87
    • 9
    • 1
    Rabbit
    Clonality
    • 83
    • 14
    Polyclonal
    Conjugate
    • 46
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This CYP3A4 antibody is un-conjugated
    Application
    • 68
    • 24
    • 20
    • 20
    • 18
    • 14
    • 13
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CYP3A4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-255 amino acids from the Central region of human CYP3A4.
    Clone
    RB15792
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CYP3A4 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    Alternative Name
    CYP3A4 (CYP3A4 Products)
    Background
    CYP3A4, is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens.
    Molecular Weight
    57343
    Gene ID
    1576
    NCBI Accession
    NP_001189784, NP_059488
    UniProt
    P08684
    Pathways
    Steroid Hormone Biosynthesis
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