Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (C-Term), (AA 458-488) antibody

Details for Product No. ABIN392274
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Antigen
Synonyms 2210420D18Rik, CARD3, CARDIAK, CCK, D4Bwg0615e, RICK, RIP2, GIG30, RIPK2
Epitope
C-Term, AA 458-488
(13), (13), (13), (5), (5), (3), (2), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(100), (41), (22), (1), (1), (1)
Host
Rabbit
(82), (14), (5)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(97), (51), (27), (24), (10), (7), (3), (2), (1), (1), (1)
Pubmed 3 references available
Catalog no. ABIN392274
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This RIPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-488 AA from the C-terminal region of human RIPK2.
Clone RB03318
Isotype Ig
Specificity This RIPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467~496 amino acids from the C-terminal region of human RIPK2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name RIPK2
Background RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
Synonyms: Receptor-interacting serine/threonine protein kinase 2, RIP-like interacting CLARP kinase, Receptor-interacting protein 2, RIP-2, CARD-containing interleukin-1 beta converting enzyme associated kinase, CARD-containing IL-1 beta ICE-kinase, RIP2
Molecular Weight 61194 DA
Gene ID 8767
UniProt NP_003812
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (C-Term), (AA 458-488) antibody Western blot analysis of anti-RIPK2 Pab (ABIN392274) in Ramos cell line lysates (35 µg/lane). RIPK2 (arrow) was detected using the purified polyclonal antibody.
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (C-Term), (AA 458-488) antibody (2) Western blot analysis of anti-RIPK2 Pab (ABIN392274) in mouse cerebellum tissue lysate. RIPK2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (C-Term), (AA 458-488) antibody (3) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma
Background publications Chin, Dempsey, Bruhn et al.: "Involvement of receptor-interacting protein 2 in innate and adaptive immune responses." in: Nature, Vol. 416, Issue 6877, pp. 190-4, 2002 (PubMed).

Munz, Hildt, Springer et al.: "RIP2, a checkpoint in myogenic differentiation." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5879-86, 2002 (PubMed).

Chen, Clark: "Equilibrium and kinetic folding of an alpha-helical Greek key protein domain: caspase recruitment domain (CARD) of RICK." in: Biochemistry, Vol. 42, Issue 20, pp. 6310-20, 2003 (PubMed).

Hosts (82), (14), (5)
Reactivities (100), (41), (22), (1), (1), (1)
Applications (97), (51), (27), (24), (10), (7), (3), (2), (1), (1), (1)
Epitopes (13), (13), (13), (5), (5), (3), (2), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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