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RIPK2 antibody

KO Validated RIPK2 Reactivity: Human WB, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856222
  • Target See all RIPK2 Antibodies
    RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
    Reactivity
    • 67
    • 37
    • 19
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Human
    Host
    • 63
    • 6
    Rabbit
    Clonality
    • 65
    • 4
    Polyclonal
    Conjugate
    • 39
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RIPK2 antibody is un-conjugated
    Application
    • 52
    • 34
    • 25
    • 9
    • 9
    • 6
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to RIP2 (receptor-interacting serine-threonine kinase 2)
    RIP2 antibody [N3C3]
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human RIP2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product RIPK2 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Raji , HeLa

    Validation: KO/KD

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2.32 mg/mL
    Buffer
    PBS, No preservative
    Preservative
    Without preservative
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
    Alternative Name
    receptor interacting serine/threonine kinase 2 (RIPK2 Products)
    Synonyms
    RIPK2 antibody, 2210420D18Rik antibody, CARD3 antibody, CARDIAK antibody, CCK antibody, D4Bwg0615e antibody, RICK antibody, RIP2 antibody, GIG30 antibody, receptor interacting serine/threonine kinase 2 antibody, receptor (TNFRSF)-interacting serine-threonine kinase 2 antibody, receptor-interacting serine-threonine kinase 2 antibody, RIPK2 antibody, Ripk2 antibody
    Background
    This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.

    Cellular Localization: Cytoplasm
    Molecular Weight
    61 kDa
    Gene ID
    8767
    UniProt
    O43353
    Pathways
    TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades
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