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RIPK2 Products

(Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

Categories

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008].

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Featured RIPK2 Categories

RIPK2 Antibodies

High quality antibodies with extensive validation data.

RIPK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

RIPK2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RIPK2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (7)
Cat. No. ABIN522206
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (6)
Cat. No. ABIN392274
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN563776
Quantity 100 μg
Datasheet Datasheet

Recommended RIPK2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969853
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962449
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380793
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended RIPK2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
Cat. No. ABIN5569595
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318112
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318114
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our RIPK2 products

Yan, Liu: "LRRK2 enhances Nod1/2-mediated inflammatory cytokine production by promoting Rip2 phosphorylation." in: Protein & cell, Vol. 8, Issue 1, pp. 55-66, (2016) (PubMed).

Eisenhardt, Habersberger, Oliva, Lancaster, Ayhan, Woollard, Bannasch, Rice, Peter: "A proteomic analysis of C-reactive protein stimulated THP-1 monocytes." in: Proteome science, Vol. 9, Issue 1, pp. 1, (2011) (PubMed).

Cirulli, Kasperaviciūte, Attix, Need, Ge, Gibson, Goldstein: "Common genetic variation and performance on standardized cognitive tests." in: European journal of human genetics : EJHG, Vol. 18, Issue 7, pp. 815-20, (2010) (PubMed).

Zhang, Huang, Chen, Sun, Liu, Li, Cui, Yan, Yang, Yang, Chu, Zhang, Zhang, Han, Yu, Quan, Yu, Zhang, Shi, Zhang, Cheng, Wang, Lin, Zheng, Fu, Zuo, Wang, Long, Sun, Cheng, Tian, Zhou, Liu, Lu, He et al.: "Genomewide association study of leprosy...." in: The New England journal of medicine, Vol. 361, Issue 27, pp. 2609-18, (2009) (PubMed).

Hosgood, Zhang, Shen, Berndt, Vermeulen, Li, Yin, Yeager, Yuenger, Rothman, Chanock, Smith, Lan: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." in: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, (2009) (PubMed).

Hasegawa, Fujimoto, Lucas, Nakano, Fukase, Núñez, Inohara: "A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation." in: The EMBO journal, Vol. 27, Issue 2, pp. 373-83, (2008) (PubMed).

Meylan, Tschopp: "The RIP kinases: crucial integrators of cellular stress." in: Trends in biochemical sciences, Vol. 30, Issue 3, pp. 151-9, (2005) (PubMed).

Lu, Wang, Dorsch, Tian, Nagashima, Coyle, Jaffee, Ocain, Xu: "Participation of Rip2 in lipopolysaccharide signaling is independent of its kinase activity." in: The Journal of biological chemistry, Vol. 280, Issue 16, pp. 16278-83, (2005) (PubMed).

Janssens, Tinel, Lippens, Tschopp: "PIDD mediates NF-kappaB activation in response to DNA damage." in: Cell, Vol. 123, Issue 6, pp. 1079-92, (2005) (PubMed).

Chen, Clark: "Equilibrium and kinetic folding of an alpha-helical Greek key protein domain: caspase recruitment domain (CARD) of RICK." in: Biochemistry, Vol. 42, Issue 20, pp. 6310-20, (2003) (PubMed).

Synonyms and alternative names related to RIPK2

receptor interacting serine/threonine kinase 2 (RIPK2), receptor (TNFRSF)-interacting serine-threonine kinase 2 (Ripk2), receptor-interacting serine-threonine kinase 2 (Ripk2), receptor interacting serine/threonine kinase 2 (Ripk2), 2210420D18Rik, CARD3, CARDIAK, CCK, D4Bwg0615e, GIG30, RICK, RIP2, RIPK2

Protein level used designations for RIPK2

  • receptor-interacting serine-threonine kinase 2
  • receptor-interacting serine/threonine-protein kinase 2-like
  • receptor-interacting serine/threonine-protein kinase 2
  • tyrosine-protein kinase RIPK2
  • CARD-carrying kinase
  • CARD-containing IL-1 beta ICE-kinase
  • CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase
  • RIP-2
  • growth-inhibiting gene 30
  • receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase
  • receptor-interacting protein 2
  • receptor (TNFRSF)-interacting serine-threonine kinase 2
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