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TCF7L1 antibody (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box)) (N-Term)

Details for Product anti-TCF7L1 Antibody No. ABIN404738, Supplier: Login to see New
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Synonyms Tcf-3, Tcf3, bHLHb21, TCF-3, TCF3, tcf3c, tcf3d, xtcf3
(9), (3), (3), (3), (2), (1), (1), (1), (1), (1)
(29), (11), (6)
(26), (2), (1)
Immunohistochemistry (IHC), Western Blotting (WB)
(27), (12), (4), (3), (2), (2)
Pubmed 1 reference available
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Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the N terminal of human TCF7L1
Blocking Peptide Blocking peptide for this product available: ABIN984906
Predicted Reactivity Guinea pig : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 80 %
Characteristics This is a rabbit polyclonal antibody against TCF7L1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TCF7L1 (TCF7L1 Antibody Abstract)
Background TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
Molecular Weight 63 kDa
Gene ID 83439
NCBI Accession NP_112573, NM_031283
UniProt Q9HCS4
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, Transcription Factors, Wnt
Pathways WNT Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 588 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-TCF7L1 antibody (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box)) (N-Term) (ABIN404738) WB Suggested Anti-TCF7L1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Immunohistochemistry (IHC) image for anti-TCF7L1 antibody (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box)) (N-Term) (ABIN404738) anti-Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1) (N-Term) antibody (Image 2)
Background publications Hillier, Graves, Fulton et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, 2005 (PubMed).

Catalog No. ABIN404738
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