Exosome Component 2 (EXOSC2) (Middle Region) antibody

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Antigen
Synonyms EXOSC2, exosc2, MGC97533, RRP4, Rrp4p, hRrp4p, p7, Rrp4, fa97b01, wu:fa97b01, zgc:110117
Epitope
Middle Region
(6), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(38), (9), (7), (1), (1)
Host
Rabbit
(22), (16)
Clonality
Polyclonal
Application
Western Blotting (WB)
(23), (15), (8), (8), (3), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human EXOSC2
Blocking Peptide Blocking peptide for this product available: Exosome Component 2 (EXOSC2) (Middle Region) peptide (ABIN976518)
Sequence AEVQAVFSDG AVSLHTRSLK YGKLGQGVLV QVSPSLVKRQ KTHFHDLPCG
Predicted Reactivity Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Human : 100 %, Mouse : 100 %, Rat : 90 %, Zebrafish : 90 %, African clawed frog : 70 %
Characteristics This is a rabbit polyclonal antibody against EXOSC2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name EXOSC2 (EXOSC2 Antibody Abstract)
Background EXOSC2 belongs to the exosome, a RNA-processing complex, which is at least involved in the 3' processing of the 7S pre-rRNA to the mature 5.8S rRNA. It exhibits a 3'-5' exoribonuclease activity.
Molecular Weight 32 kDa
Gene ID 23404
NCBI Accession NP_055100, NM_014285
UniProt Q13868
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 293 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Exosome Component 2 (EXOSC2) (Middle Region) antibody (ABIN405355) WB Suggested Anti-EXOSC2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Product cited in: van Dijk, Schilders, Pruijn: "Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, 2007 (PubMed).

Catalog No. ABIN405355
$289.00
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