Lysocardiolipin Acyltransferase 1 (LCLAT1) (Middle Region) antibody

Details for Product No. ABIN502511
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Synonyms lclat1, zgc:77380, wu:fj17g04, LYCAT, lycat, agpat8, alcat1, 1agpat8, AGPATP8, 1AGPAT8, AGPAT8, ALCAT1, HSRG1849, UNQ1849, AI181996, Agpat8, Alcat1, Gm91, Lycat, RGD1565906
Middle Region
(8), (2), (1), (1), (1)
Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(14), (1)
(1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(12), (8), (7), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the middle region of human LYCAT
Predicted Reactivity Human :100 %,   Mouse :90 %,   Pig :90 %,   Rat :90 %,  
Characteristics This is a rabbit polyclonal antibody against LYCAT. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name LYCAT (LCLAT1 Antibody Abstract)
Background LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.
Molecular Weight 44 kDa
Gene ID 253558
NCBI Accession NP_001002257, NM_001002257
UniProt B4DYR5
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 376 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Lysocardiolipin Acyltransferase 1 (LCLAT1) (Middle Region) antibody (ABIN502511) WB Suggested Anti-LYCAT Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Lysocardiolipin Acyltransferase 1 (LCLAT1) (Middle Region) antibody (ABIN502511) Host: Rabbit
Target Name: LCLAT1
Sample Tissue: Human 721_B cell
Background publications Wang, Faloon, Tan et al.: "Mouse lysocardiolipin acyltransferase controls the development of hematopoietic and endothelial lineages during in vitro embryonic stem-cell differentiation." in: Blood, Vol. 110, Issue 10, pp. 3601-9, 2007 (PubMed).

Catalog No. ABIN502511
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