LCLAT1 antibody (C-Term)

Catalog No. ABIN5530607

This Rabbit Polyclonal antibody specifically detects LCLAT1 in WB and IHC (p). It exhibits reactivity toward Mouse and Human.

Quick Overview for LCLAT1 antibody (C-Term) (ABIN5530607)

Target: LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LCLAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LCLAT1 Antibody

Binding Specificity: AA 296-324, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LCLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the C-terminal region of human LCLT1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for LCLAT1

Target: LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))

Alternative Name: LCLT1

Background: Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages.

Molecular Weight: 49 kDa

Gene ID: 253558

UniProt: Q6UWP7