CD59 antibody (PE)

Catalog No. ABIN576561

Product Details anti-CD59 Antibody (PE)

Target: CD59

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This CD59 antibody is conjugated to PE

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Clustered at the fourth leucocyte typing workshop to designation CD59(1). YTH53. Reacts with CD59 transfectants(3). It enhances antibody-mediated lysis by homologous complement(2) Reacts with GPI-linked antigen of 18-20kD size which is broadly expressed on human leucocytes and erythrocytes(2). Putative ligand for CD2.

Purification: Ion exchange chromatography

Immunogen: Human peripheral blood T cells.

Type of Immunogen: Cells

Isotype: IgG2b

Application Details

Application Notes: Approved: Flo (1:1), IHC, IHC-Fr, IHC-P, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. We do not recommend using this antibody in lysed whole blood techniques due to inhibition of staining caused by CD59 expression on erythrocytes.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.2, 0.09 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for CD59

Target: CD59

Alternative Name: CD59 (CD59 Products)

Background: Name/Gene ID: CD59

Synonyms: CD59, 16.3A5, 1F5, 1F5 antigen, CD59 glycoprotein, EL32, EJ16, G344, HRF-20, MAC-IP, MACIF, Ly-6-like protein, MEM43, MIRL, MEM43 antigen, MIN2, MIN3, MSK21, p18-20, Protectin, MAC-inhibitory protein, MIC11, T cell-activating protein, CD59 antigen, EJ30, HRF20, Human leukocyte antigen MIC11, Lymphocytic antigen CD59/MEM43, MIN1

Gene ID: 966

Pathways: Complement System