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COCH antibody (AA 141-190)

COCH Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Monkey WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6746617
  • Target See all COCH Antibodies
    COCH (Cochlin (COCH))
    Binding Specificity
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    AA 141-190
    Reactivity
    • 47
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Monkey
    Host
    • 45
    • 2
    Rabbit
    Clonality
    • 47
    Polyclonal
    Conjugate
    • 20
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COCH antibody is un-conjugated
    Application
    • 36
    • 27
    • 16
    • 13
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Specificity
    Human COCH
    Predicted Reactivity
    Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Guinea pig (100%) Horse (92%) Chicken (85%).
    Purification
    Immunoaffinity purified
    Immunogen
    Synthetic peptide located between aa141-190 of human COCH (O43405, NP_001128530). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Dog, Bovine, Rabbit, Guinea pig (100%), Elephant, Panda, Horse (92%), Bat, Opossum, Chicken, Platypus, Lizard, Xenopus (85%).

    Type of Immunogen: Synthetic peptide
    Top Product
    Discover our top product COCH Primary Antibody
  • Application Notes
    Approved: WB (0.2 - 1 μg/mL)

    Usage: Western Blot: Suggested dilution at 0.25 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Distilled water
    Concentration
    Lot specific
    Buffer
    Lyophilized from PBS with 2 % sucrose
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Anfosso, Bardin, Francès, Vivier, Camoin-Jau, Sampol, Dignat-George: "Activation of human endothelial cells via S-endo-1 antigen (CD146) stimulates the tyrosine phosphorylation of focal adhesion kinase p125(FAK)." in: The Journal of biological chemistry, Vol. 273, Issue 41, pp. 26852-6, (1998) (PubMed).

    Jean, Gershenwald, Huang, Luca, Hudson, Tainsky, Bar-Eli: "Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells." in: The Journal of biological chemistry, Vol. 273, Issue 26, pp. 16501-8, (1998) (PubMed).

    Xie, Luca, Huang, Gutman, Reich, Johnson, Bar-Eli: "Expression of MCAM/MUC18 by human melanoma cells leads to increased tumor growth and metastasis." in: Cancer research, Vol. 57, Issue 11, pp. 2295-303, (1997) (PubMed).

    Lehmann, Riethmüller, Johnson: "MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 24, pp. 9891-5, (1990) (PubMed).

  • Target
    COCH (Cochlin (COCH))
    Alternative Name
    Cochlin / COCH (COCH Products)
    Synonyms
    AW122937 antibody, Coch-5B2 antibody, D12H14S564E antibody, COCH-5B2 antibody, COCH5B2 antibody, DFNA9 antibody, cochlin antibody, Coch antibody, COCH antibody
    Background
    Name/Gene ID: COCH

    Synonyms: COCH, COCH5B2, COCH-5B2, Cochlin, DFNA9, DFNA31
    Gene ID
    1690
    NCBI Accession
    NP_001128530
    UniProt
    O43405
    Pathways
    Sensory Perception of Sound
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