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Glucose 6-Phosphatase, Catalytic (G6PC) (AA 123-149), (Center) antibody

Details for Product No. ABIN651417, Supplier: Log in to see
Antigen
  • AW107337
  • G6Pase
  • G6pt
  • Glc-6-Pase
  • G6PC1
  • G6PT
  • GSD1
  • GSD1a
  • G-6-Pase
Epitope
AA 123-149, Center
14
8
7
5
Reactivity
Human
20
4
3
1
1
1
1
Host
Rabbit
21
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
21
15
15
13
1
Supplier
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Immunogen This G6PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-149 AA from the Central region of human G6PC.
Clone RB30027
Isotype Ig
Specificity This G6PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-161 amino acids from the Central region of human G6PC.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name G6PC (G6PC Antibody Abstract)
Background Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I.
Synonyms: Glucose-6-phosphatase alpha, G6Pase-alpha, Glucose-6-phosphatase, G-6-Pase, G6Pase,G6PT, G6PC
Molecular Weight 40484 DA
Gene ID 2538
UniProt P35575
Research Area Metabolism
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 123-149), (Center) antibody (ABIN651417) Western blot analysis of G6PC Antibody (Center) (ABIN651417) in K562 cell line lysate...
Immunohistochemistry (IHC) image for anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 123-149), (Center) antibody (ABIN651417) G6PC Antibody (Center) (ABIN651417) immunohistochemistry analysis in formalin fixed a...
Flow Cytometry (FACS) image for anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 123-149), (Center) antibody (ABIN651417) G6PC Antibody (Center) (ABIN651417) flow cytometric analysis of K562 cells (right his...
Background publications Tu, Bagnall, Duflou et al.: "Post-mortem pathologic and genetic studies in "dead in bed syndrome" cases in type 1 diabetes mellitus." in: Human pathology, Vol. 41, Issue 3, pp. 392-400, 2010 (PubMed).

Samuel, Beddow, Iwasaki et al.: "Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 29, pp. 12121-6, 2009 (PubMed).