Glucose 6-Phosphatase, Catalytic (G6PC) (AA 123-149), (Center) antibody

Details for Product No. ABIN651417
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Synonyms AW107337, G6Pase, G6pt, Glc-6-Pase, G6PC1, G6PT, GSD1, GSD1a, G-6-Pase
AA 123-149, Center
(4), (1)
(19), (17), (15), (13), (13), (13), (1)
(23), (2)
Clonality (Clone)
Polyclonal ()
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(16), (11), (10), (9), (6), (6), (1), (1)
Pubmed 2 references available
Catalog no. ABIN651417
Quantity 400 µL
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Immunogen This G6PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-149 AA from the Central region of human G6PC.
Clone RB30027
Isotype Ig
Specificity This G6PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-161 amino acids from the Central region of human G6PC.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name G6PC
Background Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I.
Synonyms: Glucose-6-phosphatase alpha, G6Pase-alpha, Glucose-6-phosphatase, G-6-Pase, G6Pase,G6PT, G6PC
Molecular Weight 40484 DA
Gene ID 2538
UniProt P35575
Research Area Metabolism
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 123-149), (Center) antibody Western blot analysis of G6PC Antibody (Center) (ABIN651417) in K562 cell line lysates (35 µg/lane).G6PC (arrow) was detected using the purified polyclonal antibody.
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 123-149), (Center) antibody (2) G6PC Antibody (Center) (ABIN651417) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 123-149), (Center) antibody (3) G6PC Antibody (Center) (ABIN651417) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Samuel, Beddow, Iwasaki et al.: "Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 29, pp. 12121-6, 2009 (PubMed).

Tu, Bagnall, Duflou et al.: "Post-mortem pathologic and genetic studies in "dead in bed syndrome" cases in type 1 diabetes mellitus." in: Human pathology, Vol. 41, Issue 3, pp. 392-400, 2010 (PubMed).

Hosts (23), (2)
Reactivities (19), (17), (15), (13), (13), (13), (1)
Applications (16), (11), (10), (9), (6), (6), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (1)
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