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Details for Product No. ABIN652730

Xeroderma Pigmentosum, Complementation Group A (XPA) (C-Term), (AA 221-250) antibody

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Synonyms XP1, XPAC, Xpac, AI573865, CG6358, DhR14, DhXPA, DmXPA, Dmel\\CG6358, Dxpa, EG:EG0007.8, XPA_DROME, Xpa, dmXPA, dxpa, xpac, xxpa
»Alternatives C-Term, AA 221-250
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN652730
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This XPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-250 AA from the C-terminal region of human XPA.
Clone RB23644
Isotype Ig
Specificity This XPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228~258 amino acids from the C-term region of human XPA .
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name XPA
Background XPA is involved in DNA excision repair. It initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. This protein is required for UV-induced CHK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.
Synonyms: Xeroderma pigmentosum group A-complementing protein, DNA repair protein complementing XP-A cells, XPA, XPAC
Molecular Weight 31368 DA
Gene ID 7507
UniProt P23025
Research Area Signaling, Neurology
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications States, McDuffie, Myrand et al.: "Distribution of mutations in the human xeroderma pigmentosum group A gene and their relationships to the functional regions of the DNA damage recognition protein." in: Human mutation, Vol. 12, Issue 2, pp. 103-13, 1998 (PubMed).

Alternatives for antigen "Xeroderma Pigmentosum, Complementation Group A (XPA)", type "Antibodies"
Hosts (33), (20)
Reactivities (53), (13), (3)
Applications (52), (22), (11), (11), (6), (4), (3), (2), (2), (1), (1), (1)
Epitopes (10), (5), (2), (1), (1), (1), (1), (1)