XPA Products
(Xeroderma Pigmentosum, Complementation Group A (XPA))
Categories
This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009].
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Featured XPA Categories
XPA Antibodies
High quality antibodies with extensive validation data.
XPA ELISA Kits
Reliable ELISA kits for a wide range of species.
XPA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended XPA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), IP, ICC
Validations
- (1)
- (4)
Cat. No.
ABIN2855566
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN948624
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN652730
Quantity
400 μL
Datasheet
Datasheet
Recommended XPA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381596
Quantity
96 tests
Datasheet
Datasheet
Recommended XPA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325438
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3075637
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422931
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our XPA products
: "Transcriptional consequences of XPA disruption in human cell lines." in: DNA repair, Vol. 57, pp. 76-90, (2017) (PubMed).: "Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites." in: Nucleic acids research, Vol. 44, Issue 3, pp. e27, (2016) (PubMed).
: "HCMV-infected cells maintain efficient nucleotide excision repair of the viral genome while abrogating repair of the host genome." in: PLoS pathogens, Vol. 8, Issue 11, pp. e1003038, (2012) (PubMed).
: "Inhibition of nucleotide excision repair by anti-XPA monoclonal antibodies which interfere with binding to RPA, ERCC1, and TFIIH." in: Biochemical and biophysical research communications, Vol. 321, Issue 4, pp. 815-22, (2004) (PubMed).
: "Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome." in: Molecular and cellular biology, Vol. 21, Issue 7, pp. 2281-91, (2001) (PubMed).
: "Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein." in: The EMBO journal, Vol. 16, Issue 3, pp. 625-38, (1997) (PubMed).
: "Mammalian DNA nucleotide excision repair reconstituted with purified protein components." in: Cell, Vol. 80, Issue 6, pp. 859-68, (1995) (PubMed).
: "Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain." in: Nature, Vol. 348, Issue 6296, pp. 73-6, (1990) (PubMed).
Synonyms and alternative names related to XPA
Xeroderma pigmentosum group A-like (Xpac), XPA, DNA damage recognition and repair factor (XPA), xeroderma pigmentosum, complementation group A (Xpa), XPA, DNA damage recognition and repair factor (Xpa), xeroderma pigmentosum, complementation group A L homeolog (xpa.L), AI573865, CG6358, DhR14, DhXPA, Dmel\\CG6358, DmXPA, dmXPA, Dxpa, dxpa, EG:EG0007.8, XP1, Xpa, XPAC, Xpac, xpac, XPA_DROME, xxpaProtein level used designations for XPA
- CG6358-PA
- Xpac-PA
- xeroderma pigmentosum group A-like
- DNA repair protein complementing XP-A cells
- excision repair-controlling
- xeroderma pigmentosum group A-complementing protein
- DNA repair protein complementing XP-A cells homolog
- xeroderma pigmentosum group A-complementing protein homolog
- xpacch protein
- xpacx1 protein
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