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UNC13B antibody (AA 1062-1091)

UNC13B Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB22476 unconjugated
Catalog No. ABIN652852
  • Target See all UNC13B Antibodies
    UNC13B (Unc-13 Homolog B (UNC13B))
    Binding Specificity
    • 8
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1062-1091
    Reactivity
    • 31
    • 18
    • 2
    Human
    Host
    • 40
    • 2
    • 1
    Rabbit
    Clonality
    • 42
    • 1
    Polyclonal
    Conjugate
    • 19
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UNC13B antibody is un-conjugated
    Application
    • 31
    • 26
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Predicted Reactivity
    M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1062-1091 amino acids from the Central region of human UNC13B.
    Clone
    RB22476
    Isotype
    Ig Fraction
    Top Product
    Discover our top product UNC13B Primary Antibody
  • Application Notes
    WB: 1:1000. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Kasmapour, Gronow, Bleck, Hong, Gutierrez: "Size-dependent mechanism of cargo sorting during lysosome-phagosome fusion is controlled by Rab34." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 50, pp. 20485-90, (2012) (PubMed).

  • Target
    UNC13B (Unc-13 Homolog B (UNC13B))
    Alternative Name
    UNC13B (UNC13B Products)
    Synonyms
    MUNC13 antibody, UNC13 antibody, Unc13h2 antibody, UNC13B antibody, Munc13-2 antibody, Munc13-1 antibody, Unc13a antibody, Unc13h1 antibody, unc-13 homolog B antibody, unc-13 homolog B (C. elegans) antibody, UNC13B antibody, Unc13b antibody
    Background
    UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).
    Molecular Weight
    180679
    Gene ID
    10497
    NCBI Accession
    NP_006368
    UniProt
    O14795
    Pathways
    Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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