Unc-13 Homolog B (C. Elegans) (UNC13B) (AA 1062-1091), (Center) antibody

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Synonyms UNC13B, MUNC13, UNC13, Unc13h2, Munc13-1, Munc13-2, Unc13a, Unc13h1
AA 1062-1091, Center
(32), (15), (15), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
(58), (40), (18), (2)
(67), (11), (5)
Clonality (Clone)
Polyclonal ()
(8), (8), (8), (7), (7), (7), (1), (1), (1), (1), (1), (1), (1), (1)
Flow Cytometry (FACS), Western Blotting (WB)
(65), (49), (10), (9), (7), (4), (3), (2), (2), (1)
Pubmed 2 references available
Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1062-1091 AA from the Central region of human UNC13B.
Clone RB22476
Isotype Ig
Specificity This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1069~1099 amino acids from the Center region of human UNC13B.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name UNC13B (UNC13B Antibody Abstract)
Background UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).
Synonyms: Munc13-2, munc13, Protein unc-13 homolog B, UNC13B, UNC13
Molecular Weight 180679 DA
Gene ID 10497
UniProt O14795
Research Area Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Unc-13 Homolog B (C. Elegans) (UNC13B) (AA 1062-1091), (Center) antibody (ABIN652852) Western blot analysis of UNC13B Antibody (Center) (ABIN652852) in 293 cell line lysat...
Flow Cytometry (FACS) image for anti-Unc-13 Homolog B (C. Elegans) (UNC13B) (AA 1062-1091), (Center) antibody (ABIN652852) UNC13B Antibody (Center) (ABIN652852) flow cytometric analysis of 293 cells (right hi...
Product cited in: Kasmapour, Gronow, Bleck et al.: "Size-dependent mechanism of cargo sorting during lysosome-phagosome fusion is controlled by Rab34." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 50, pp. 20485-90, 2012 (PubMed).

Background publications Sjöblom, Jones, Wood et al.: "The consensus coding sequences of human breast and colorectal cancers. ..." in: Science (New York, N.Y.), Vol. 314, Issue 5797, pp. 268-74, 2006 (PubMed).

Catalog No. ABIN652852
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