NEIL1 antibody (AA 130-159)

Catalog No. ABIN653649

Product Details anti-NEIL1 Antibody

Target: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Binding Specificity: AA 130-159

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEIL1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This NEIL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human NEIL1.

Clone: RB18510

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for NEIL1

Target: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Alternative Name: NEIL1 (NEIL1 Products)

Synonyms: FPG1 antibody, NEI1 antibody, hFPG1 antibody, 2810450N13Rik antibody, Nei1 antibody, nei-like DNA glycosylase 1 antibody, nei like DNA glycosylase 1 antibody, nei endonuclease VIII-like 1 (E. coli) antibody, Neil1 antibody, NEIL1 antibody

Background: NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).

Molecular Weight: 43684

Gene ID: 79661

NCBI Accession: NP_001243481, NP_078884

UniProt: Q96FI4

Pathways: DNA Damage Repair