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Details for Product No. ABIN654695

SEC13 Homolog (S. Cerevisiae) (SEC13) (AA 72-100), (Center) antibody

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Antigen
Synonyms SEC13R, npp-20, SEC13L1, D3S1231E, Sec13r, Sec13l1, 1110003H02Rik
Epitope
»Alternatives AA 72-100, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 3 references available
Catalog no. ABIN654695
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This SEC13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-100 AA from the Central region of human SEC13.
Clone RB23825
Isotype Ig
Specificity This SEC13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the Central region of human SEC13.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SEC13
Background The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found.
Synonyms: Protein SEC13 homolog,SEC13,D3S1231E, SEC13L1, SEC13R
Molecular Weight 35541 DA
Gene ID 6396
UniProt NP_899195.1, P55735
Research Area Signaling, Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Glavy, Krutchinsky, Cristea et al.: "Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 10, pp. 3811-6, 2007 (PubMed).

Hsia, Stavropoulos, Blobel et al.: "Architecture of a coat for the nuclear pore membrane." in: Cell, Vol. 131, Issue 7, pp. 1313-26, 2007 (PubMed).

Nielsen: "The coat protein complex II, COPII, protein Sec13 directly interacts with presenilin-1." in: Biochemical and biophysical research communications, Vol. 388, Issue 3, pp. 571-5, 2009 (PubMed).

Alternatives for antigen "SEC13 Homolog (S. Cerevisiae) (SEC13)", type "Antibodies"
Hosts (9), (4)
Reactivities (13), (2), (2)
Applications (11), (6), (3), (3), (2), (2), (1), (1)
Epitopes (3), (2), (1), (1), (1), (1)
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