SEC13 antibody

Catalog No. ABIN7118814

Product Details anti-SEC13 Antibody

Target: SEC13 (SEC13 Homolog (SEC13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: SEC13 homolog(S. cerevisiae)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for SEC13

Target: SEC13 (SEC13 Homolog (SEC13))

Alternative Name: SEC13 (SEC13 Products)

Synonyms: D3S1231E antibody, SEC13L1 antibody, SEC13R antibody, npp-20 antibody, 1110003H02Rik antibody, Sec13l1 antibody, Sec13r antibody, Protein SEC13 homolog antibody, SEC13 homolog, nuclear pore and COPII coat complex component antibody, npp-20 antibody, SEC13 antibody, Sec13 antibody

Background: Synonyms:D3S1231E, SEC13L1, SEC13R Background:Functions as a component of the nuclear pore complex(NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway. Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream and is regulated by amino acid sensors like SESN2(Probable).

Molecular Weight: 36 kDa

Gene ID: 6396

UniProt: P55735