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Details for Product No. ABIN655508

Deoxynucleotidyltransferase, terminal (DNTT) (C-Term), (AA 438-467) antibody

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Synonyms TDT, Tdt, BB160593, dntt-A, TdT
»Alternatives C-Term, AA 438-467
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN655508
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This TdT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-467 AA from the C-terminal region of human TdT.
Clone RB18827
Isotype Ig
Specificity This TdT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-475 amino acids from the C-terminal region of human TdT.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name TdT
Background This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Synonyms: DNA nucleotidylexotransferase,DNTT,TDT
Molecular Weight 58536 DA
Gene ID 1791
UniProt NP_001017520.1, NP_004079.3, P04053
Research Area Cell Structure, Signaling, Protein Modifications, Chromatin
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Liu, McGavran, Lovell et al.: "Nonpositive terminal deoxynucleotidyl transferase in pediatric precursor B-lymphoblastic leukemia." in: American journal of clinical pathology, Vol. 121, Issue 6, pp. 810-5, 2004 (PubMed).

Alternatives for antigen "Deoxynucleotidyltransferase, terminal (DNTT)", type "Antibodies"
Hosts (76), (27)
Reactivities (90), (23), (23), (14), (5), (4), (1), (1)
Applications (50), (32), (13), (10), (9), (8), (5), (3), (2), (2), (2), (1), (1)
Conjugates (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (15), (10), (4), (2), (2), (2), (1), (1), (1), (1)