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Details for Product No. ABIN655599

Ephrin B2 (EFNB2) (AA 157-186), (Center) antibody

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Antigen
Synonyms EPLG5, HTKL, Htk-L, LERK5, Epl5, ELF-2, Eplg5, Lerk5, LERK-5, NLERK-1, EFNB2, efnb2, ephrin-B2, htkl, eplg5, htk-l, lerk5, ephrinB2, efnb2a, MGC68890, efnb2b
Epitope
»Alternatives AA 157-186, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
Pubmed 1 reference available
Catalog no. ABIN655599
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This EFNB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 AA from the Central region of human EFNB2.
Clone RB31411
Isotype Ig
Specificity This EFNB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-194 amino acids from the Central region of human EFNB2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name EFNB2
Background This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.
Synonyms: Ephrin-B2,EFNB2,EPLG5, HTKL, LERK5
Pathways: Axon guidance
Molecular Weight 36923 Da
Gene ID 1948
UniProt P52799
Research Area Cell Structure, Neurology, Protein Modifications, Cell Cycle, Cell Signaling, Phospho-specific antibodies
Application Notes Recommend dilutions: IHC : 1:10-50,WB : 1:1000,IF : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.47 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Qin, Noberini, Huan et al.: "Structural characterization of the EphA4-Ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity." in: The Journal of biological chemistry, Vol. 285, Issue 1, pp. 644-54, 2009 (PubMed).

Alternatives for antigen "Ephrin B2 (EFNB2)", type "Antibodies"
Hosts (41), (7), (1)
Reactivities (45), (32), (18), (1), (1), (1)
Applications (47), (12), (7), (7), (3), (2)
Epitopes (7), (7), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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