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Ephrin B2 Products

(Ephrin B2 (EFNB2))
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008].

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Featured Ephrin B2 Categories

Ephrin B2 Antibodies

High quality antibodies with extensive validation data.

Ephrin B2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Ephrin B2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Ephrin B2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (37)
Cat. No. ABIN6261455
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7151879
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN655599
Quantity 400 μL
Datasheet Datasheet

Recommended Ephrin B2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955613
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955614
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6974781
Quantity 96 tests
Datasheet Datasheet

Recommended Ephrin B2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274531
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1352413
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320517
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Ephrin B2 products

Coucha, Barrett, Elgebaly, Ergul, Abdelsaid: "Inhibition of Ephrin-B2 in brain pericytes decreases cerebral pathological neovascularization in diabetic rats." in: PLoS ONE, Vol. 14, Issue 1, pp. e0210523, (2019) (PubMed).

Shi, Wang, Peng, Qi, Vitale, Kaneda, Murata, Luo, Wu: "EPHB6 controls catecholamine biosynthesis by up-regulating tyrosine hydroxylase transcription in adrenal gland chromaffin cells." in: The Journal of biological chemistry, Vol. 294, Issue 17, pp. 6871-6887, (2019) (PubMed).

Hampton-ONeil, Severn, Cross, Gurung, Nobes, Toye: "Ephrin/Eph receptor interaction facilitates macrophage recognition of differentiating human erythroblasts." in: Haematologica, (2019) (PubMed).

Grandi, Zini, Palese, Giorgio, Tognolini, Marchesani, Bruno, Flammini, Cantoni, Castelli, Lodola, Fusari, Barocelli, Bertoni: "Targeting the Eph/Ephrin System as Anti-Inflammatory Strategy in IBD." in: Frontiers in pharmacology, Vol. 10, pp. 691, (2019) (PubMed).

Toray, Hasegawa, Sakagami, Tsuchiya, Kudo, Zhao, Moritani, Abe, Yoshida, Yamamoto, Yamamoto, Oda, Udagawa, Luiz de Freitas, Li: "Histochemical assessment for osteoblastic activity coupled with dysfunctional osteoclasts in c-src deficient mice." in: Biomedical research (Tokyo, Japan), Vol. 38, Issue 2, pp. 123-134, (2018) (PubMed).

Wong, Young, Zhang, Liu, Leser, Komives, Lamb, Zhou, Salafsky, Jardetzky: "Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation." in: Nature communications, Vol. 8, Issue 1, pp. 781, (2018) (PubMed).

Lagares, Ghassemi-Kakroodi, Tremblay, Santos, Probst, Franklin, Santos, Grasberger, Ahluwalia, Montesi, Shea, Black, Knipe, Blati, Baron, Wu, Fahmi, Gandhi, Pardo, Selman, Wu, Pelletier et al.: "ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis. ..." in: Nature medicine, Vol. 23, Issue 12, pp. 1405-1415, (2017) (PubMed).

Tsang, Hyun, Cheng, Vargas, Mehta, Ushio-Fukai, Zou, Pajcini, Rehman, Malik: "Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1α." in: Stem cell reports, Vol. 9, Issue 3, pp. 796-806, (2017) (PubMed).

Depner, Zum Buttel, Böğürcü, Cuesta, Aburto, Seidel, Finkelmeier, Foss, Hofmann, Kaulich, Barbus, Segarra, Reifenberger, Garvalov, Acker, Acker-Palmer: "EphrinB2 repression through ZEB2 mediates tumour invasion and anti-angiogenic resistance." in: Nature communications, Vol. 7, pp. 12329, (2016) (PubMed).

Caporali, Meloni, Nailor, Mitić, Shantikumar, Riu, Sala-Newby, Rose, Besnier, Katare, Voellenkle, Verkade, Martelli, Madeddu, Emanueli: "p75(NTR)-dependent activation of NF-κB regulates microRNA-503 transcription and pericyte-endothelial crosstalk in diabetes after limb ischaemia." in: Nature communications, Vol. 6, pp. 8024, (2015) (PubMed).

Synonyms and alternative names related to Ephrin B2

ephrin B2 (EFNB2), ephrin-B2 precursor (efnb2), ephrin B2 (efnb2), ephrin B2 L homeolog (efnb2.L), ephrin B2 S homeolog (efnb2.S), ephrin B2 (Efnb2), EFNB2, efnb2, efnb2a, efnb2b, ELF-2, ephrin-B2, ephrinB2, Epl5, eplg5, Eplg5, EPLG5, htk-l, Htk-L, htkl, HTKL, LERK-5, lerk5, Lerk5, LERK5, MGC68890, NLERK-1

Protein level used designations for Ephrin B2

  • ephrin-B2
  • ephrin-B2 precursor
  • ephrin B2
  • ephrin-B2a
  • ephrin-B2b
  • EPH-related receptor tyrosine kinase ligand 5
  • HTK ligand
  • LERK-5
  • eph-related receptor tyrosine kinase ligand 5
  • ligand of eph-related kinase 5
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