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AKR1C2 antibody (Aldo-keto Reductase Family 1, Member C2) (AA 296-323)

Details for Product anti-AKR1C2 Antibody No. ABIN656180, Supplier: Log in to see
Antigen
  • AKR1C-pseudo
  • BABP
  • DD
  • DD2
  • DDH2
  • HAKRD
  • HBAB
  • MCDR2
  • SRXY8
  • Akr1c21
Epitope
AA 296-323, C-Term
15
15
12
5
5
4
3
3
2
1
1
1
1
Reactivity
Human
60
1
1
1
Host
Rabbit
46
14
Clonality (Clone)
Polyclonal ()
Conjugate
This AKR1C2 antibody is un-conjugated
3
3
3
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
58
37
17
3
3
2
1
Supplier
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Immunogen This AKR1C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-323 AA from the C-terminal region of human AKR1C2.
Clone RB32249
Isotype Ig
Specificity This AKR1C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-323 amino acids from the C-terminal region of human AKR1C2.
Predicted Reactivity Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name AKR1C2 (AKR1C2 Antibody Abstract)
Background This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Synonyms: AKR1C2,Aldo-keto reductase family 1 member C2,DDH2
Molecular Weight 36735 DA
Gene ID 1646
NCBI Accession NP_995317
UniProt P52895
Research Area Signaling, Protein Modifications, Metabolism, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.45 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment AKR1C2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-AKR1C2 antibody (Aldo-keto Reductase Family 1, Member C2) (AA 296-323) (ABIN656180) AKR1C2 Antibody (C-term) (ABIN656180) immunohistochemistry analysis in formalin fixed...
Background publications Wang, Chorley, Pittman et al.: "Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer." in: PLoS ONE, Vol. 5, Issue 8, pp. e11934, 2010 (PubMed).