AKR1C2 antibody (AA 1-323)

Catalog No. ABIN514925

There is 1 publication for this product available. The Mouse Polyclonal anti-AKR1C2 antibody is suitable to detect AKR1C2 in samples from Human. It has been validated for WB.

Quick Overview for AKR1C2 antibody (AA 1-323) (ABIN514925)

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This AKR1C2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AKR1C2 Antibody

Binding Specificity: AA 1-323

Purpose: Mouse polyclonal antibody raised against a full-length human AKR1C2 protein.

Sequence: MDSKYQCVKL NDGHFMPVLG FGTYAPAEVP KSKALEAVKL AIEAGFHHID SAHVYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV SVKPGEEVIP KDENGKILFD TVDLCATWEA MEKCKDAGLA KSIGVSNFNH RLLEMILNKP GLKYKPVCNQ VECHPYFNQR KLLDFCKSKD IVLVAYSALG SHREEPWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTS EEMKAIDGLN RNVRYLTLDI FAGPPNYPFS DEY

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: AKR1C2 (AAH07024.1, 1 a.a. ~ 323 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-AKR1C2 antibody (ABIN514925)

Ebert, Kisiela, Wsól, Maser: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).

Target Details for AKR1C2

Target: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Alternative Name: AKR1C2

Background: Full Gene Name: aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2, bile acid binding protein, 3-alpha hydroxysteroid dehydrogenase, type III)
Synonyms: AKR1C-pseudo,BABP,DD,DD2,DDH2,HAKRD,HBAB,MCDR2

Gene ID: 1646

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process