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AKR1C2 antibody

AKR1C2 Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal CPTC-AKR1C2-1 unconjugated
Catalog No. ABIN6939232
  • Target See all AKR1C2 Antibodies
    AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
    Reactivity
    • 46
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 40
    • 6
    Mouse
    Clonality
    • 43
    • 3
    Monoclonal
    Conjugate
    • 26
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKR1C2 antibody is un-conjugated
    Application
    • 36
    • 25
    • 16
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant human full-length AKR1C2 protein
    Clone
    CPTC-AKR1C2-1
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product AKR1C2 Primary Antibody
  • Application Notes

    Positive Control: HeLa, K-562, A431, HepG2, A549 cells. Human liver or stomach tissue.

    Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
    Alternative Name
    AKR1C2 (AKR1C2 Products)
    Synonyms
    AKR1C-pseudo antibody, BABP antibody, DD antibody, DD2 antibody, DDH2 antibody, HAKRD antibody, HBAB antibody, MCDR2 antibody, SRXY8 antibody, Akr1c21 antibody, aldo-keto reductase family 1 member C2 antibody, aldo-keto reductase family 1, member C2 antibody, AKR1C2 antibody, Akr1c2 antibody
    Background
    DDH2 / AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.
    Molecular Weight
    37kDa
    Gene ID
    1646
    UniProt
    P52895
    Pathways
    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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