Glutaryl-CoA Dehydrogenase (GCDH) (C-Term), (AA 336-365) antibody

Details for Product No. ABIN656829
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Antigen
Epitope
C-Term, AA 336-365
(12), (10), (8), (3), (1), (1)
Reactivity
Human
(40), (17), (16), (2), (2)
Host
Rabbit
(39), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(32), (16), (12), (10), (6), (3), (3), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 400 μL
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Catalog No. ABIN656829
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Immunogen This GCDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 AA from the C-terminal region of human GCDH.
Clone RB20979
Isotype Ig
Specificity This GCDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-365 amino acids from the C-terminal region of human GCDH.
Predicted Reactivity Cow (Bovine),Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name GCDH
Background The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms: Glutaryl-CoA dehydrogenase, mitochondrial,GCDH,
Molecular Weight 48127 DA
Gene ID 2639
NCBI Accession NP_000150, NP_039663
UniProt Q92947
Research Area Cell Signaling, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment GCDH Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Glutaryl-CoA Dehydrogenase (GCDH) (C-Term), (AA 336-365) antibody GCDH Antibody (C-term) (ABIN656829) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Background publications Ganesh, Zakai, van Rooij et al.: "Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium...." in: Nature genetics, Vol. 41, Issue 11, pp. 1191-8, 2009 (PubMed).

Validation Images
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