GCDH Products
(Glutaryl-CoA Dehydrogenase (GCDH))
Categories
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013].
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Featured GCDH Categories
GCDH Antibodies
High quality antibodies with extensive validation data.
GCDH ELISA Kits
Reliable ELISA kits for a wide range of species.
GCDH Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GCDH Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7445012
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IP
Validations
- (4)
Cat. No.
ABIN7154056
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN515979
Quantity
50 μg
Datasheet
Datasheet
Recommended GCDH ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN5594801
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1134990
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6230119
Quantity
96 tests
Datasheet
Datasheet
Recommended GCDH Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354902
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123126
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3080487
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GCDH products
: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
Synonyms and alternative names related to GCDH
glutaryl-CoA dehydrogenase (GCDH), glutaryl-CoA dehydrogenase (Gcdh), glutaryl-CoA dehydrogenase a (gcdha), glutaryl-Coenzyme A dehydrogenase (Gcdh), 9030411L18, ACAD5, AI266902, D17825, GCD, zgc:56505, zgc:77704Protein level used designations for GCDH
- glutaryl-CoA dehydrogenase, mitochondrial
- glutaryl-Coenzyme A dehydrogenase
- GCD
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