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Details for Product No. ABIN657662

CD27 Molecule (CD27) (C-Term), (AA 196-225) antibody

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Synonyms S152, S152. LPFS2, T14, TNFRSF7, Tp55, Tnfrsf7
»Alternatives C-Term, AA 196-225
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 3 references available
Catalog no. ABIN657662
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This CD27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-225 AA from the C-terminal region of human CD27.
Clone RB33726
Isotype Ig
Specificity This CD27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-225 amino acids from the C-terminal region of human CD27.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CD27
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Synonyms: CD27 antigen,CD27,TNFRSF7
Molecular Weight 29137 DA
Gene ID 939
UniProt NP_001233.1, P26842
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Application Notes Recommend dilutions: WB : 1:1000,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.49 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment CD27 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Arimoto-Miyamoto, Kadowaki, Kitawaki et al.: "Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4(+) T-cell differentiation." in: Immunology, Vol. 130, Issue 1, pp. 137-49, 2010 (PubMed).

Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Mizuochi, Ito, Saito et al.: "Possible recruitment of peripheral blood CXCR3+ CD27+ CD19+ B cells to the liver of chronic hepatitis C patients." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 30, Issue 4, pp. 243-52, 2010 (PubMed).

Alternatives for antigen "CD27 Molecule (CD27)", type "Antibodies"
Hosts (106), (54), (38), (4), (3), (1), (1)
Reactivities (172), (82), (39), (17), (17), (17), (9)
Applications (166), (28), (28), (24), (22), (10), (10), (9), (9), (6), (6), (4), (2), (2), (2), (1)
Conjugates (25), (20), (16), (12), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (4), (2), (1), (1), (1)