CD27 Products
(CD27 Molecule (CD27))
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008].
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Featured CD27 Categories
CD27 Antibodies
High quality antibodies with extensive validation data.
CD27 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD27 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD27 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (6)
Cat. No.
ABIN560236
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
FACS, ELISA, IHC, IF, StM, Coat
Validations
- (8)
Cat. No.
ABIN6941124
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (5)
Cat. No.
ABIN7259975
Quantity
200 μL
Datasheet
Datasheet
Recommended CD27 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954502
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1889312
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1672775
Quantity
96 tests
Datasheet
Datasheet
Recommended CD27 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274108
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274113
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274097
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD27 products
: "Dimerization interface of osteoprotegerin revealed by hydrogen-deuterium exchange mass spectrometry." in: The Journal of biological chemistry, Vol. 293, Issue 45, pp. 17523-17535, (2019) (PubMed).: "Expression of CD70 in nasal natural killer/T cell lymphoma cell lines and patients; its role for cell proliferation through binding to soluble CD27." in: British journal of haematology, Vol. 160, Issue 3, pp. 331-42, (2013) (PubMed).
: "CD27 expression discriminates porcine T helper cells with functionally distinct properties." in: Veterinary research, Vol. 44, pp. 18, (2013) (PubMed).
: "Assessment of the phenotype and functionality of porcine CD8 T cell responses following vaccination with live attenuated classical swine fever virus (CSFV) and virulent CSFV challenge." in: Clinical and vaccine immunology : CVI, Vol. 20, Issue 10, pp. 1604-16, (2013) (PubMed).
: "Porcine CD27: identification, expression and functional aspects in lymphocyte subsets in swine." in: Developmental and comparative immunology, Vol. 38, Issue 2, pp. 321-31, (2012) (PubMed).
: "Expression of soluble CD27 and interleukins-8 and -10 in B-cell chronic lymphocytic leukemia: correlation with disease stage and prognosis." in: Advances in therapy, Vol. 24, Issue 1, pp. 29-40, (2007) (PubMed).
: "Blockade of protease-activated receptors on T cells correlates with altered proteolysis of CD27 by gingipains of Porphyromonas gingivalis." in: Clinical and experimental immunology, Vol. 150, Issue 2, pp. 217-29, (2007) (PubMed).
: "IL-7 decreases IL-7 receptor alpha (CD127) expression and induces the shedding of CD127 by human CD8+ T cells." in: International immunology, Vol. 19, Issue 12, pp. 1329-39, (2007) (PubMed).
Synonyms and alternative names related to CD27
CD27 molecule (CD27), CD27 antigen (Cd27), CD27 molecule (Cd27), S152, S152. LPFS2, T14, TNFRSF7, Tnfrsf7, Tp55Protein level used designations for CD27
- tumor necrosis factor receptor superfamily, member 7
- CD27 antigen
- CD27L receptor
- CD antigen 27
- T-cell activation antigen CD27
- tumor necrosis factor receptor superfamily member 7
- T cell activation antigen S152
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