You are viewing an incomplete version of our website. Please click to reload the website as full version.

Retinoblastoma Binding Protein 8 antibody (RBBP8) (AA 763-792)

Details for Product anti-RBBP8 Antibody No. ABIN657950, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms CtIP, RBBP8, RBBP-8, RIM, SAE2, DKFZp469K0714, COM1, CTIP, JWDS, SCKL2, 9930104E21Rik, RGD1308872
AA 763-792, C-Term
(27), (15), (10), (6), (5), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
(97), (29), (16), (4), (1)
(84), (9), (4)
Clonality (Clone)
Polyclonal ()
This Retinoblastoma Binding Protein 8 antibody is un-conjugated
(3), (3), (3), (3), (3), (3), (1)
Western Blotting (WB)
(70), (54), (27), (10), (7), (7), (5), (2), (2), (1), (1), (1)
Pubmed 2 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This RBBP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 763-792 AA from the C-terminal region of human RBBP8.
Clone RB34059
Isotype Ig
Specificity This RBBP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 762-792 amino acids from the C-terminal region of human RBBP8.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RBBP8 (RBBP8 Antibody Abstract)
Background The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Synonyms: DNA endonuclease RBBP8,5932,CTIP
Molecular Weight 101942 DA
Gene ID 5932
NCBI Accession NP_976037, NP_976036, NP_002885
UniProt Q99708
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Protein Modifications, Cell Cycle, Transcription Factors, Chromatin, Signaling, Metabolism, Cell Structure
Pathways Cell Division Cycle, DNA Damage Repair
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment RBBP8 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Retinoblastoma Binding Protein 8 antibody (RBBP8) (AA 763-792) (ABIN657950) RBBP8 Antibody (C-term) (ABIN657950) western blot analysis in CEM cell line lysates (...
Background publications Kaidi, Weinert, Choudhary et al.: "Human SIRT6 promotes DNA end resection through CtIP deacetylation." in: Science (New York, N.Y.), Vol. 329, Issue 5997, pp. 1348-53, 2010 (PubMed).

Thye, Vannberg, Wong et al.: "Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2." in: Nature genetics, Vol. 42, Issue 9, pp. 739-41, 2010 (PubMed).

Catalog No. ABIN657950
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)