Calreticulin antibody (AA 101-200)
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- Target See all Calreticulin (CALR) Antibodies
- Calreticulin (CALR)
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Binding Specificity
- AA 101-200
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Calreticulin antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Calreticulin
- Isotype
- IgG
- Top Product
- Discover our top product CALR Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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Immunogenic cell death due to a new photodynamic therapy (PDT) with glycoconjugated chlorin (G-chlorin)." in: Oncotarget, Vol. 7, Issue 30, pp. 47242-47251, (2016) (PubMed).
: "Calreticulin Binds to Fas Ligand and Inhibits Neuronal Cell Apoptosis Induced by Ischemia-Reperfusion Injury." in: BioMed research international, Vol. 2015, pp. 895284, (2015) (PubMed).
: "Complementary induction of immunogenic cell death by oncolytic parvovirus H-1PV and gemcitabine in pancreatic cancer." in: Journal of virology, Vol. 88, Issue 10, pp. 5263-76, (2014) (PubMed).
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Immunogenic cell death due to a new photodynamic therapy (PDT) with glycoconjugated chlorin (G-chlorin)." in: Oncotarget, Vol. 7, Issue 30, pp. 47242-47251, (2016) (PubMed).
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- Target
- Calreticulin (CALR)
- Alternative Name
- Calreticulin (CALR Products)
- Background
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Synonyms: RO, CRT, SSA, cC1qR, HEL-S-99n, Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 6, ERp6, HACBP, grp6, CALR, CRTC
Background: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).
- Gene ID
- 811
- UniProt
- P27797
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
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