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Thrombomodulin antibody

THBD Reactivity: Human, Rabbit FACS, IHC (p), IHC (fro) Host: Mouse Monoclonal QBEND-40 unconjugated
Catalog No. ABIN6653774
  • Target See all Thrombomodulin (THBD) Antibodies
    Thrombomodulin (THBD)
    Reactivity
    • 104
    • 36
    • 19
    • 3
    • 1
    • 1
    Human, Rabbit
    Host
    • 67
    • 50
    • 6
    • 2
    Mouse
    Clonality
    • 66
    • 58
    • 1
    Monoclonal
    Conjugate
    • 59
    • 17
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Thrombomodulin antibody is un-conjugated
    Application
    • 80
    • 47
    • 45
    • 39
    • 26
    • 22
    • 21
    • 15
    • 14
    • 12
    • 11
    • 11
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purification
    Tissue Culture Supernatant containing 0.2M Tris/HCl pH7.4 and 5-10% foetal calf serum
    Immunogen
    Human Endothelium (Thrombomodulin).
    Clone
    QBEND-40
    Isotype
    IgG2a
    Top Product
    Discover our top product THBD Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody undiluted at -20 °C.
  • Target
    Thrombomodulin (THBD)
    Alternative Name
    CD141 / THBD (THBD Products)
    Background
    CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII, thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.Synonyms: Fetomodulin, THRM, Thrombomodulin
    Gene ID
    9606
    UniProt
    P07204
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