Thrombomodulin antibody (AA 200-500)
Quick Overview for Thrombomodulin antibody (AA 200-500) (ABIN1683026)
Target
See all Thrombomodulin (THBD) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 200-500
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Sequence
- RGADFQALPV GSSAAVAPLG LQLMCTAPPG AVQGHWAREA PGAWDCSVEN GGCEHACNAI PGAPRCQCPA GAALQADGRS CTASATQSCN DLCEHFCVPN PDQPGSYSCM CETGYRLAAD QHRCEDVDDC ILEPSPCPQR CVNTQGGFEC HCYPNYDLVD GECVEPVDPC FRANCEYQCQ PLNQTSYLCV CAEGFAPIPH EPHRCQMFCN QTACPADCDP NTQASCECPE GYILDDGFIC TDIDECENGG FCSGVCHNLP GTFECICGPD SALARHIGTD CDSGKVDGGD SGSGEPPPSP T
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human THBD (NP_000352.1).
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Isotype
- IgG
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Application Notes
- WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Thrombomodulin (THBD)
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Alternative Name
- THBD
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Background
- The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.,THBD,AHUS6,BDCA3,CD141,THPH12,THRM,TM,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Cardiovascular,Cardiovascular Markers,Endothelial Cells,Blood,Coagulation,THBD
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Molecular Weight
- 60 kDa
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Gene ID
- 7056
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UniProt
- P07204
Target
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