Integrin beta 3 antibody
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- Target See all Integrin beta 3 (ITGB3) Antibodies
- Integrin beta 3 (ITGB3)
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Reactivity
- Human, Primate
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Integrin beta 3 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- This antibody detects CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, Non-Human Primates
- Purification
- Protein-A affinity chromatography
- Purity
- > 95 % pure by SDS-PAGE
- Clone
- VIPL2
- Isotype
- IgG1
- Top Product
- Discover our top product ITGB3 Primary Antibody
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anti-Integrin beta 3 (ITGB3) (AA 134-376) antibody
ITGB3 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 27-120) antibodyITGB3 Reactivity: Human, Mouse WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 27-179) antibodyITGB3 Reactivity: Human FACS, IHC, ELISA Host: Mouse Monoclonal 3E8A6 unconjugated
anti-Integrin beta 3 (ITGB3) antibodyITGB3 Reactivity: Human WB, IHC, IP Host: Rabbit Monoclonal unconjugated
anti-Integrin beta 3 (ITGB3) antibody (FITC)ITGB3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal VIPL2 FITC
anti-Integrin beta 3 (ITGB3) antibody (PerCP)ITGB3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal VIPL2 PerCP
anti-Integrin beta 3 (ITGB3) (AA 385-490) antibodyITGB3 Reactivity: Human IHC, StM Host: Mouse Monoclonal ITGB3-2145 unconjugated
anti-Integrin beta 3 (ITGB3) (AA 610-718) antibodyITGB3 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 734-760) antibodyITGB3 Reactivity: Human WB, FACS, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) antibodyITGB3 Reactivity: Human, Non-Human Primate WB, FACS, IHC (fro) Host: Mouse Monoclonal VIPL2 unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- Target
- Integrin beta 3 (ITGB3)
- Alternative Name
- CD61 / ITGB3 (ITGB3 Products)
- Background
- CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 Molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
- Gene ID
- 3690
- NCBI Accession
- NP_000203
- UniProt
- P05106
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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