DCMP Deaminase (DCTD) (N-Term), (AA 1-30) antibody

Details for Product No. ABIN951852
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Antigen
Synonyms 6030466N05Rik, DCTD, zgc:110226, DKFZp459M1226, Afu2g06240, MGC81193
Epitope
N-Term, AA 1-30
(2), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(16), (2), (2)
Host
Rabbit
(10), (6)
Clonality
Polyclonal
Application
ELISA, Western Blotting (WB)
(15), (8), (2), (2), (2), (1), (1)
Pubmed 3 references available
Catalog no. ABIN951852
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
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Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Human DCTD. Genename: DCTD
Specificity This antibody recognizes Human DCTD (N-term).
Purification Affinity Chromatography on Protein A
Alternative Name DCTD
Background The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene
Alternate names: Deoxycytidylate deaminase, dCMP deaminase
Molecular Weight 20016 Da
Gene ID 1635
NCBI Accession NP_001012750
Research Area Chromatin and Nuclear Signaling
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Rha, Jeung, Choi et al.: "An association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients." in: The oncologist, Vol. 12, Issue 6, pp. 622-30, 2007 (PubMed).

Okazaki, Javle, Tanaka et al.: "Single nucleotide polymorphisms of gemcitabine metabolic genes and pancreatic cancer survival and drug toxicity." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 1, pp. 320-9, 2010 (PubMed).

Hosts (10), (6)
Reactivities (16), (2), (2)
Applications (15), (8), (2), (2), (2), (1), (1)
Epitopes (2), (2), (2), (1), (1), (1), (1)
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