DCMP Deaminase (DCTD) (Middle Region) antibody

Catalog No. ABIN2784643

This Rabbit Polyclonal antibody specifically detects DCMP Deaminase in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse and Rabbit.

Quick Overview for DCMP Deaminase (DCTD) (Middle Region) antibody (ABIN2784643)

Target: DCMP Deaminase (DCTD)

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: Middle Region

Purpose: DCTD Antibody - middle region

Sequence: MSDKYHDSDE ATAARLLFNM AGVTFRKFIP KCSKIVIDFD SINSRPSQKL

Predicted Reactivity: Cow: 100%, Dog: 86%, Goat: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DCTD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DCTD

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51821-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: DCMP Deaminase (DCTD)

Alternative Name: DCTD

Background:

Background Information: The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: DCMP deaminase

Alternative Symbols: MGC111062

Protein Name: Deoxycytidylate deaminase

Molecular Weight: 21kDa

Gene ID: 1635

NCBI Accession: NP_001012750

UniProt: D3DP49