Erythropoietin (EPO) (N-Term), (AA 19-48) antibody

Details for Product No. ABIN952117
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Antigen
Synonyms EPO, EP, MVCD2
Epitope
N-Term, AA 19-48
(14), (8), (7), (7), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(172), (25), (23), (13), (12), (12), (4), (1), (1), (1)
Host
Rabbit
(102), (79), (5), (2), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(12), (9), (6), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(131), (122), (18), (13), (10), (8), (7), (7), (4), (3), (3), (2), (2), (2), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN952117
357.50 $
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Immunogen KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of Human Erythropoietin. Genename: EPO
Specificity This antibody recognizes Human and Mouse Erythropoietin / EPO (N-term).
Purification Affinity Chromatography on Protein A
Alternative Name Erythropoietin / EPO
Background EPO is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. [provided by RefSeq].
Alternate names: Epoetin
Molecular Weight 21307 Da
Gene ID 2056
NCBI Accession NP_000790
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Shi, Hodges, Dunlop et al.: "Erythropoietin-induced activation of the JAK2/STAT5, PI3K/Akt, and Ras/ERK pathways promotes malignant cell behavior in a modified breast cancer cell line." in: Molecular cancer research : MCR, Vol. 8, Issue 4, pp. 615-26, 2010 (PubMed).

Carraway, Suliman, Jones et al.: "Erythropoietin activates mitochondrial biogenesis and couples red cell mass to mitochondrial mass in the heart." in: Circulation research, Vol. 106, Issue 11, pp. 1722-30, 2010 (PubMed).

Kristensen, Pedersen-Bjergaard, Schalkwijk et al.: "Erythropoietin and vascular endothelial growth factor as risk markers for severe hypoglycaemia in type 1 diabetes." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 163, Issue 3, pp. 391-8, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Kim, Cho, Huh et al.: "Transduction of human EPO into human bone marrow mesenchymal stromal cells synergistically enhances cell-protective and migratory effects." in: Molekuliarnaia biologiia, Vol. 44, Issue 4, pp. 656-63, 2010 (PubMed).

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