EPO antibody

Catalog No. ABIN969109

Product Details anti-EPO Antibody

Target: EPO (Erythropoietin (EPO))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPO antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: purified

Immunogen: Purified recombinant fragment of human EPO expressed in E. coli.

Clone: 4F11

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-EPO antibody (ABIN969109)

Hirschler-Laszkiewicz, Tong, Conrad, Zhang, Flint, Barber, Barber, Cheung, Miller: "TRPC3 activation by erythropoietin is modulated by TRPC6." in: The Journal of biological chemistry, Vol. 284, Issue 7, pp. 4567-81, (2009) (PubMed).

Target Details for EPO

Target: EPO (Erythropoietin (EPO))

Alternative Name: EPO (EPO Products)

Synonyms: EPO antibody, EP antibody, MVCD2 antibody, erythropoietin antibody, erythropoietin S homeolog antibody, erythropoietin a antibody, EPO antibody, epo antibody, epo.S antibody, Epo antibody, epoa antibody

Target Type: Hormone

Background:

Description: Human erythropoietin is member of the EPO/TPO family and encodes a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.Tissue specificity: Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.

Aliases: EP, MVCD2, MGC138142, EPO

Molecular Weight: 21 kDa

Gene ID: 2056

HGNC: 2056

Pathways: JAK-STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity