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Folate Receptor 2 (Fetal) (FOLR2) (AA 16-44), (N-Term) antibody

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Synonyms FOLR2, BETA-HFR, FBP, FBP/PL-1, FR-BETA, FR-P3, FBP2, Folbp-2, Folbp2
N-Term, AA 16-44
(28), (15), (9), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
(53), (6), (2)
(40), (12), (1)
(5), (4), (3), (3), (3), (3), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(46), (30), (13), (12), (5), (5), (4), (2), (2), (1)
Pubmed 2 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 16-44 amino acids from the N-terminal region of Human Folate receptor beta Genename: FOLR2
Isotype Ig
Specificity This antibody recognizes Human Folate receptor beta (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name Folate Receptor beta (FOLR2 Antibody Abstract)
Background The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.Synonyms: FOLR2, FR-beta, Folate receptor 2, Placental folate-binding protein
Molecular Weight 29280 Da
Gene ID 2350
NCBI Accession NP_001107008
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Folate Receptor 2 (Fetal) (FOLR2) (AA 16-44), (N-Term) antibody (ABIN952352) Western blot analysis of Folate receptor beta Antibody (N-term) in MDA-MB453, NCI-H46...
Background publications OByrne, Au, Morrison et al.: "Association of folate receptor (FOLR1, FOLR2, FOLR3) and reduced folate carrier (SLC19A1) genes with meningomyelocele." in: Birth defects research. Part A, Clinical and molecular teratology, Vol. 88, Issue 8, pp. 689-94, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Catalog No. ABIN952352
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