FOLR2 antibody (Internal Region)

Catalog No. ABIN6261780

Product Details anti-FOLR2 Antibody

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: FOLR2 Antibody detects endogenous levels of total FOLR2.

Predicted Reactivity: Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FOLR2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for FOLR2

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Alternative Name: FOLR2 (FOLR2 Products)

Synonyms: FOLR2 antibody, BETA-HFR antibody, FBP antibody, FBP/PL-1 antibody, FR-BETA antibody, FR-P3 antibody, FBP2 antibody, Folbp-2 antibody, Folbp2 antibody, folate receptor 1 antibody, folate receptor beta antibody, folate receptor 2 (fetal) antibody, FOLR1 antibody, FOLR2 antibody, Folr2 antibody

Background:

Description: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral  pH . Exposure to slightly acidic  pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.

Gene: FOLR2

Molecular Weight: 29 kDa

Gene ID: 2350

UniProt: P14207

Pathways: Dicarboxylic Acid Transport